Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21589722 | 0.96 | USP2 (0.30) | LTB4R2USP2ALDH1A1POLBALOX15 | |
| SCHEMBL21589514 | 0.90 | RORC (0.31) | — | |
| SCHEMBL21589718 | 0.89 | NR1H4 (0.36) | — | |
| SCHEMBL21589626 | 0.87 | RORC (0.30) | — | |
| SCHEMBL21589772 | 0.85 | — | — | |
| SCHEMBL21589858 | 0.85 | — | — | |
| SCHEMBL23481680 | 0.85 | PTGDR2 (0.35) | TSHRHSD17B10 | |
| SCHEMBL21586028 | 0.85 | DRD2 (0.33) | USP2ALDH1A1POLBALOX15TSHR | |
| SCHEMBL22476248 | 0.83 | NR1H4 (0.32) | LTB4R2 | |
| SCHEMBL21589790 | 0.83 | SLC10A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802504-B1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2023-01-18 | — | — | EP | disclosed |
| WO-2019234077-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2019-12-12 | — | — | WO | disclosed |