⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21592244 | 0.71 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL21591499 | 0.62 | CYP11B1 (0.51) | — | |
| SCHEMBL30132324 | 0.61 | KDM4E (0.31) | — | |
| SCHEMBL21591514 | 0.60 | CYP11B1 (0.40) | — | |
| SCHEMBL930156 | 0.60 | CYP19A1 (0.57) | — | |
| SCHEMBL21591470 | 0.58 | CYP1A2 (0.39) | — | |
| SCHEMBL10090899 | 0.56 | HTR1A (0.38) | — | |
| SCHEMBL21591490 | 0.56 | CYP3A4 (0.52) | — | |
| SCHEMBL19688317 | 0.54 | HRH1 (0.52) | — | |
| SCHEMBL10851197 | 0.54 | MAPT (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807264-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2021-04-21 | — | — | EP | disclosed |
| WO-2019238786-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2019-12-19 | — | — | WO | disclosed |