Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1820528 | 0.92 | HRH1 (0.58) | HRH1LOXL2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11922727 | 0.89 | HRH1 (0.46) | HRH1LOXL2MAPT | |
| SCHEMBL4726195 | 0.88 | LOXL2 (0.52) | HRH1LOXL2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4205219 | 0.83 | HRH1 (0.51) | HRH1 | |
| SCHEMBL713426 | 0.81 | MAPT (0.55) | MAPT | |
| SCHEMBL1685452 | 0.79 | CARM1 (0.53) | — | |
| SCHEMBL27946217 | 0.78 | CYP2A6 (0.61) | HRH1CYP1A2CYP3A4CYP2D6CYP2A6 | |
| SCHEMBL21444971 | 0.78 | LOXL2 (0.50) | HRH1LOXL2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27971485 | 0.77 | HRH1 (0.53) | HRH1LOXL2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10851197 | 0.76 | MAPT (0.61) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11241014-B2 | Antimicrobial coatings and methods of making and using thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2022-02-08 | — | — | US | disclosed |
| US-20200281205-A1 | ANTIMICROBIAL COATINGS AND METHODS OF MAKING AND USING THEREOF | NATIONAL SCIENCE FOUNDATION | 2020-09-10 | — | — | US | disclosed |
| US-20180030165-A1 | Polycations and Methods of Making and Using Thereof | NATIONAL SCIENCE FOUNDATION | 2018-02-01 | — | — | US | disclosed |
| WO-2017210347-A1 | ANTIMICROBIAL COATINGS AND METHODS OF MAKING AND USING THEREOF | GEORGIA TECH RESEARCH CORPORATION (US) | 2017-12-07 | — | — | WO | disclosed |
| CN-103459573-B | Balanced dynamic mixtures for controlled release of perfuming aldehydes and ketones | FIRMENICH S.A. (CH) | 2015-11-25 | — | — | CN | disclosed |
| CN-103459573-A | Balanced dynamic mixtures for controlled release of perfuming aldehydes and ketones | FIRMENICH & CIE | 2013-12-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200281205-A1 | ANTIMICROBIAL COATINGS AND METHODS OF MAKING AND USING THEREOF | MPO, LPO, CUTA | HRH1 3702/4885LOXL2 738/4885CYP1A2 3698/4885 |
| US-11241014-B2 | Antimicrobial coatings and methods of making and using thereof | MPO, LPO, CUTA | HRH1 3702/4885LOXL2 738/4885CYP1A2 3698/4885 |
| US-20180030165-A1 | Polycations and Methods of Making and Using Thereof | POLI, PARG, PCNA | HRH1 4652/4885LOXL2 4731/4885CYP1A2 4789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.