Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21593329 | 0.85 | ALDH1A1 (0.38) | GAAERN1HTR2AALDH1A1CYP1A2 | |
| SCHEMBL31689789 | 0.65 | MC4R (0.40) | HTR2AALDH1A1 | |
| SCHEMBL28855352 | 0.64 | PDE4A (0.47) | GAAERN1 | |
| SCHEMBL15525407 | 0.63 | NQO2 (0.47) | ERN1ALDH1A1 | |
| SCHEMBL16475647 | 0.62 | ERN1 (0.68) | ERN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL24169418 | 0.59 | KMT2A (0.38) | GAAERN1HTR2AALDH1A1 | |
| SCHEMBL27933933 | 0.59 | CYP1A2 (0.41) | GAAERN1HTR2AALDH1A1CYP1A2 | |
| SCHEMBL7617001 | 0.59 | — | — | |
| SCHEMBL6672627 | 0.58 | NQO2 (0.47) | ERN1ALDH1A1 | |
| SCHEMBL12561405 | 0.58 | ALOX15 (0.50) | ERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238424-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2019-12-19 | — | — | WO | disclosed |