Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.40 |
| ▸ | FLT3 | P36888 | 5/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24976174 | 0.84 | PRMT5 (0.39) | PRMT5WDR77FLT3KDRKDM4E | |
| SCHEMBL24760197 | 0.83 | ALB (0.34) | PRMT5WDR77FLT3KDRKIT | |
| SCHEMBL24760193 | 0.82 | FLT3 (0.34) | PRMT5WDR77FLT3KDRKIT | |
| SCHEMBL21863416 | 0.80 | FLT3 (0.48) | PRMT5WDR77FLT3KDRKDM4E | |
| SCHEMBL23107182 | 0.77 | KIT (0.45) | PRMT5WDR77FLT3KDRKDM4E | |
| SCHEMBL24976169 | 0.76 | PRMT5 (0.36) | PRMT5WDR77FLT3KDRKDM4E | |
| SCHEMBL20721438 | 0.75 | FLT3 (0.38) | PRMT5WDR77FLT3KDRKDM4E | |
| SCHEMBL24976620 | 0.75 | KIT (0.39) | PRMT5WDR77FLT3KDM4EHPGD | |
| SCHEMBL24247713 | 0.74 | PRMT5 (0.40) | PRMT5WDR77FLT3KDRKDM4E | |
| SCHEMBL23107175 | 0.74 | CHRNB2 (0.43) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238424-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2019-12-19 | — | — | WO | disclosed |