SCHEMBL2159347

SCHEMBL2159347

O=C(CCl)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL20546734 0.97
SCHEMBL11575966 0.78
SCHEMBL5861177 0.78
SCHEMBL31636148 0.75
SCHEMBL11725437 0.75
SCHEMBL3679168 0.73 TSHR (0.33)
SCHEMBL8691775 0.73 TSHR (0.40)
SCHEMBL183178 0.72 PLOD2 (0.46)
SCHEMBL11533523 0.72 FAAH (0.57)
Hydrochloric Acid SCHEMBL3679173 0.71 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977918-A Synthesis method of 2-bromomethyl-5-trifluoromethyl furan 上海高准医药有限公司 2025-05-13 CN claimed
CN-108314664-B Method for preparing 3,3, 3-trifluoro-1, 2-epoxypropane 浙江蓝天环保高科技股份有限公司 2020-10-09 CN claimed
CN-108314664-A A method of preparing tri- fluoro- 1,2 epoxy prapanes of 3,3,3- 浙江蓝天环保高科技股份有限公司 2018-07-24 CN claimed
EP-1127865-B1 Process for producing 1,1,1-Trifluoroacetone CENTRAL GLASS CO LTD (JP) 2005-11-02 EP claimed
US-6340776-B2 HYROGENOLYSIS OF HALOGENATED TRIFLUOROACETONE BY HYDROGEN GAS IN PRESENCE OF TRANSITION METAL CATALYST CENTRAL GLASS COMPANY, LIMITED (JP) 2002-01-22 US claimed
US-20010037041-A1 Process for producing 1,1,1,-trifluoroacetone CENTRAL GLASS COMPANY, LIMITED (JP) 2001-11-01 US claimed
EP-1127865-A1 Process for producing 1,1,1-Trifluoroacetone Central Glass Company, Limited (JP) 2001-08-29 EP claimed
EP-0872468-B1 Method for producing 3,3-dichloro-1,1,1-trifluoroacetone CENTRAL GLASS CO LTD (JP) 2001-07-25 EP claimed
US-5905174-A FLUORINATING PENTACHLOROACETONE WITH HYDROGEN FLUORIDE IN THE PRESENCE OF A CATALYST CENTRAL GLASS COMPANY, LIMITED (JP) 1999-05-18 US claimed
EP-0872468-A1 Method for producing 3,3-dichloro-1,1,1-trifluoroacetone Central Glass Company, Limited (JP) 1998-10-21 EP claimed
EP-0866064-A1 Improved process for the preparation of trifluoromethyloxirane BAYER AG (DE) 1998-09-23 EP claimed
JP-10330308-A None JP disclosed
JP-10279571-A None JP disclosed
US-12583870-B2 Azaheteroaryl compound and application thereof SHANGHAI BLUERAY BIOPHARMA CO., LTD. (CN) 2026-03-24 US disclosed
EP-4680333-A1 PHENYLPIPERIDINE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEIN Boehringer Ingelheim International GmbH (DE) 2026-01-21 EP disclosed
EP-0866064-A1 Improved process for the preparation of trifluoromethyloxirane BAYER AG (DE) 1998-09-23 EP disclosed
EP-0866064-A1 Improved process for the preparation of trifluoromethyloxirane BAYER AG (DE) 1998-09-23 EP disclosed
US-5739394-A 3,3-dioxy-4,4,4-trifluorobutyric acid derivatives BAYER AKTIENGESELLSCHAFT (DE) 1998-04-14 US disclosed
EP-0780362-A1 3,3-Dioxy-4,4,4-trifluorobutyric acid derivatives BAYER AG (DE) 1997-06-25 EP disclosed
WO-1996034866-A1 IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-11-07 WO disclosed