Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.44 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898697 | 0.92 | MAPT (0.51) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL21667796 | 0.88 | MAPT (0.54) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30427506 | 0.85 | MEN1 (0.53) | MAPTALDH1A1MEN1KMT2AGPR119 | |
| SCHEMBL21590381 | 0.85 | EGLN2 (0.44) | GPR119 | |
| SCHEMBL23560863 | 0.81 | MAPT (0.48) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL23560709 | 0.81 | MEN1 (0.56) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL31490530 | 0.79 | LMNA (0.53) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL21590374 | 0.78 | ALDH1A1 (0.55) | MAPTALDH1A1GPR119HTT | |
| SCHEMBL12070614 | 0.78 | MAPT (0.50) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL18087219 | 0.78 | ALDH1A1 (0.57) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238629-A1 | PYRIDINYL HETEROCYCLYL COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2019-12-19 | — | — | WO | disclosed |