SCHEMBL21596793

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21596867	0.85	KDR (0.56)	FYNFGFR1KDRFLT3MAP4K2
	SCHEMBL29652439	0.85	KDR (0.56)	FYNFGFR1KDRFLT3MAP4K2
	SCHEMBL21596901	0.82	NPC1 (0.48)	ALDH1A1KDM4EHSD17B10NPC1RAB9A
	SCHEMBL29652491	0.82	NPC1 (0.48)	ALDH1A1KDM4EHSD17B10NPC1RAB9A
	SCHEMBL21596927	0.77	FYN (0.41)	FYNFLT3PDGFRBPDGFRAALDH1A1
	SCHEMBL21608946	0.75	KAT7 (0.36)	FYNFGFR1KDRFLT3MAP4K2
	SCHEMBL21596906	0.75	GLRA3 (0.36)	FGFR1KDRFLT3MAP4K2ROCK1
	SCHEMBL1781983	0.74	KDR (0.50)	FYNFGFR1KDRFLT3MAP4K2
	SCHEMBL27176094	0.74	HPGD (0.49)	ALDH1A1KDM4EHSD17B10MEN1KMT2A
	SCHEMBL21609236	0.74	KAT6A (0.66)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.