Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.56 |
| ▸ | FLT3 | P36888 | 4/20 | 0.56 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.56 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.56 |
| ▸ | PIM1 | P11309 | 2/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.56 |
| ▸ | PRKACA | P17612 | 2/20 | 0.56 |
| ▸ | LTK | P29376 | 2/20 | 0.56 |
| ▸ | GRK5 | P34947 | 2/20 | 0.56 |
| ▸ | CDK8 | P49336 | 2/20 | 0.56 |
| ▸ | CDK7 | P50613 | 2/20 | 0.56 |
| ▸ | CDK9 | P50750 | 2/20 | 0.56 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.56 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.56 |
| ▸ | MST1R | Q04912 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29652439 | 1.00 | KDR (0.56) | KDRFLT3ACVR1FGFR1MAP4K2 | |
| SCHEMBL21596793 | 0.85 | FYN (0.44) | KDRFLT3ACVR1FGFR1MAP4K2 | |
| SCHEMBL21596912 | 0.80 | FYN (0.46) | KDRFLT3ACVR1FGFR1MAP4K2 | |
| SCHEMBL21660538 | 0.78 | KAT6A (0.61) | — | |
| Hydrochloric Acid SCHEMBL31535978 | 0.78 | CYP3A4 (0.40) | KDRFLT3ACVR1FGFR1MAP4K2 | |
| SCHEMBL29652491 | 0.74 | NPC1 (0.48) | ALDH1A1GAAMAPT | |
| SCHEMBL21596901 | 0.74 | NPC1 (0.48) | ALDH1A1GAAMAPT | |
| SCHEMBL26074223 | 0.73 | ADORA2A (0.47) | ALKKITMAPT | |
| SCHEMBL1781983 | 0.73 | KDR (0.50) | KDRFLT3ACVR1FGFR1MAP4K2 | |
| SCHEMBL22954804 | 0.71 | CYP3A4 (0.69) | ACVR1FYNBMPR1ATGFBR1ACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062393-A1 | Compounds | CTXT PTY LTD (AU) | 2026-03-05 | — | — | US | disclosed |
| EP-3810602-B1 | COMPOUNDS | CTXT PTY LTD (AU) | 2023-11-01 | — | — | EP | disclosed |
| US-20220153710-A1 | Compounds | CTXT PTY LTD (AU) | 2022-05-19 | — | — | US | disclosed |
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| US-20200039945-A1 | Compounds | CTXT PTY LIMITED (AU) | 2020-02-06 | — | — | US | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153710-A1 | Compounds | SLC10A1, ABCB11, PCSK9 | KDR 4509/4885FLT3 2102/4885ACVR1 2540/4885 |
| US-20200039945-A1 | Compounds | SLC10A1, ABCB11, PCSK9 | KDR 4505/4885FLT3 2101/4885ACVR1 2536/4885 |
| US-20260062393-A1 | Compounds | SCN2B, ABCB11, SCN1B | KDR 1022/4885FLT3 2336/4885ACVR1 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.