SCHEMBL21596796

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21596874	0.83	PIK3CD (0.43)	MAPK14F9PIK3CDPI4KAPIK3CG
	SCHEMBL29652589	0.83	PIK3CD (0.43)	MAPK14F9PIK3CDPI4KAPIK3CG
	SCHEMBL14072365	0.78	MAP4K4 (0.52)	MAPK14F9F11DYRK1A
	SCHEMBL15638775	0.77	FEN1 (0.49)	MAPK14F9GSK3BKITKDR
	SCHEMBL21596858	0.76	BRD4 (0.41)	MAPK14F9GSK3BKDRF11
	SCHEMBL13376464	0.74	MAP4K4 (0.58)	MAPK14F9GSK3BKITKDR
	SCHEMBL21596920	0.73	PIK3CD (0.43)	PIK3CDPIP5K1CPI4KAPIK3CGPI4KB
	SCHEMBL7072970	0.73	MAP4K4 (0.46)	MAPK14F9KITKDRFLT3
	SCHEMBL8276224	0.73	MAP4K4 (0.42)	MAPK14F9F11
	SCHEMBL12441328	0.73	F11 (0.46)	MAPK14F9GSK3BF11ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.