Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596921 | 0.83 | PIK3CD (0.47) | PIK3CDPI4KAPIK3CGPI4KBLMNA | |
| SCHEMBL21596918 | 0.76 | BRD4 (0.39) | BRD4PIM1 | |
| SCHEMBL21596796 | 0.73 | MAPK14 (0.42) | PIK3CDPIP5K1CPI4KAPIK3CGPI4KB | |
| SCHEMBL15922137 | 0.72 | KMT2A (0.41) | DYRK1ALMNAMAPTMEN1HTT | |
| SCHEMBL21596940 | 0.69 | ENPP2 (0.45) | LMNAMAPTMEN1HSP90AA1HTT | |
| SCHEMBL16208442 | 0.66 | TDP1 (0.56) | PIK3CDPIP5K1CPI4KAPIK3CGPI4KB | |
| Hydrochloric Acid SCHEMBL6648426 | 0.66 | RAB9A (0.46) | PI4KAPI4KBBRD4LMNAMAPT | |
| SCHEMBL17691844 | 0.66 | PIK3CD (0.44) | PIK3CDPIP5K1CPI4KAPIK3CGPI4KB | |
| SCHEMBL17229023 | 0.66 | CLK4 (0.42) | PIK3CDPIP5K1CPI4KAPIK3CGPI4KB | |
| SCHEMBL13615869 | 0.66 | CLK4 (0.42) | PIK3CDPIP5K1CPI4KAPIK3CGPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |