Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 4/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.46 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596927 | 0.85 | FYN (0.41) | FYNFLT3PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL21596867 | 0.80 | KDR (0.56) | FYNACVR1BMPR1ATGFBR1ACVRL1 | |
| SCHEMBL29652439 | 0.80 | KDR (0.56) | FYNACVR1BMPR1ATGFBR1ACVRL1 | |
| SCHEMBL21596911 | 0.74 | NPC1 (0.48) | ALDH1A1GAAMAPTPIK3CDCYP1A1 | |
| SCHEMBL21596932 | 0.73 | DCPS (0.51) | ALDH1A1GAA | |
| SCHEMBL22954804 | 0.71 | CYP3A4 (0.69) | FYNACVR1BMPR1ATGFBR1ACVRL1 | |
| SCHEMBL21596930 | 0.70 | NQO2 (0.41) | PIM1MAP4K2AURKBALDH1A1MAPT | |
| SCHEMBL21596936 | 0.70 | ALDH1A1 (0.33) | ALDH1A1GAA | |
| SCHEMBL21596916 | 0.67 | MLYCD (0.32) | ALDH1A1GAA | |
| SCHEMBL29431753 | 0.67 | KDM1A (0.57) | FYNACVR1BMPR1ATGFBR1ACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |