SCHEMBL21596898

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18215048	0.86	TRPV4 (0.46)	KDM4EALDH1A1HPGDHSD17B10GAA
	SCHEMBL12763649	0.80	TRPV4 (0.42)	EGLN2KDM4EALDH1A1TRPV4TDP1
	SCHEMBL18500978	0.79	ALDH1A1 (0.41)	KDM4EALDH1A1HPGDHSD17B10GAA
	SCHEMBL21596899	0.79	TRPV4 (0.41)	EGLN2TRPV4L3MBTL1MEN1KMT2A
	Hydrochloric Acid SCHEMBL20840161	0.77	TRPV4 (0.40)	EGLN2ALDH1A1TRPV4BACE1L3MBTL1
	SCHEMBL16109779	0.76	MAPT (0.39)	EGLN2KDM4EALDH1A1HPGDHSD17B10
	SCHEMBL16082317	0.75	TRPV4 (0.52)	EGLN2TRPV4
	SCHEMBL15716060	0.75	ALDH1A1 (0.36)	EGLN2KDM4EALDH1A1HPGDHSD17B10
	SCHEMBL862662	0.73	TRPV4 (0.50)	EGLN2TRPV4
	SCHEMBL30583466	0.73	TRPV4 (0.50)	EGLN2TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.