Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596927 | 0.82 | FYN (0.41) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL29652491 | 0.80 | NPC1 (0.48) | NPC1ALDH1A1MAPTERN1PDE4A | |
| SCHEMBL21596901 | 0.80 | NPC1 (0.48) | NPC1ALDH1A1MAPTERN1PDE4A | |
| SCHEMBL21596912 | 0.74 | FYN (0.46) | ALDH1A1MAPTGAACYP1A1CYP1A2 | |
| SCHEMBL12317970 | 0.73 | ALDH1A1 (0.65) | NPC1ALDH1A1MAPTERN1SMN1; SMN2 | |
| SCHEMBL29496942 | 0.73 | ALDH1A1 (0.65) | NPC1ALDH1A1MAPTERN1SMN1; SMN2 | |
| SCHEMBL21596921 | 0.72 | PIK3CD (0.47) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6766750 | 0.72 | ALDH1A1 (0.59) | NPC1ALDH1A1MAPTERN1PDE4A | |
| SCHEMBL7727602 | 0.71 | ERN1 (0.57) | NPC1ALDH1A1MAPTERN1PDE4A | |
| SCHEMBL27539112 | 0.71 | ERN1 (0.74) | NPC1ALDH1A1MAPTERN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |