Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596939 | 0.74 | PTGS1 (0.30) | — | |
| SCHEMBL29652416 | 0.73 | KDR (0.37) | NQO2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL21596851 | 0.73 | KDR (0.37) | NQO2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL24344354 | 0.70 | NQO2 (0.41) | NQO2MEN1KMT2AMAPTALOX5AP | |
| SCHEMBL30770136 | 0.70 | TDP2 (0.45) | NQO2ALOX5APFEN1TDP2 | |
| SCHEMBL21596942 | 0.69 | BACE1 (0.40) | CA4 | |
| SCHEMBL21596932 | 0.69 | DCPS (0.51) | NQO2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL21596930 | 0.67 | NQO2 (0.41) | NQO2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL1519286 | 0.66 | ALOX5AP (0.40) | NQO2MEN1KMT2ARAB9AMAPT | |
| SCHEMBL29514108 | 0.66 | ALOX5AP (0.40) | NQO2MEN1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |