Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 3/20 | 0.35 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.34 |
| ▸ | MAP3K9 | P80192 | 2/20 | 0.34 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596936 | 0.76 | ALDH1A1 (0.33) | ALDH1A1POLBCA4 | |
| SCHEMBL21596910 | 0.75 | CA4 (0.30) | CA4 | |
| SCHEMBL21596927 | 0.75 | FYN (0.41) | MAPTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL21596934 | 0.75 | ALDH1A1 (0.34) | ALDH1A1KDM4EPOLBCA4 | |
| SCHEMBL21608946 | 0.73 | KAT7 (0.36) | NQO2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL21596916 | 0.73 | MLYCD (0.32) | ALDH1A1CA4TSHR | |
| SCHEMBL21596932 | 0.72 | DCPS (0.51) | NQO2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21596912 | 0.70 | FYN (0.46) | MAPTALDH1A1PIM1AURKBMAP4K2 | |
| SCHEMBL21596911 | 0.70 | NPC1 (0.48) | MAPTRAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL18305802 | 0.70 | DCPS (0.57) | NQO2MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |