Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2159683 | 0.84 | MAPK1 (0.41) | MAPK1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL2161013 | 0.77 | MAPK1 (0.52) | MAPK1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL2159802 | 0.77 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL12336849 | 0.77 | L3MBTL1 (0.38) | MAPK1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL1282528 | 0.72 | L3MBTL1 (0.55) | MAPK1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL9635979 | 0.71 | L3MBTL1 (0.54) | MAPK1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL2160987 | 0.69 | MEN1 (0.47) | MAPK1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL12336846 | 0.69 | MEN1 (0.47) | MAPK1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL2161023 | 0.69 | MEN1 (0.31) | MEN1KMT2ATDP1 | |
| SCHEMBL12336850 | 0.69 | HSP90AB1 (0.34) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183842-A1 | Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them | BASF SE (DE) | 2011-07-28 | — | — | US | disclosed |
| EP-2346838-A1 | TRIAZOLE AND IMIDAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING THEM | BASF SE (DE) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010040718-A1 | TRIAZOLE AND IMIDAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING THEM | BASF SE (DE) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183842-A1 | Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them | OAT, ABAT, TYR | MAPK1 1464/4885MEN1 1942/4885KMT2A 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.