SCHEMBL2159769

SCHEMBL2159769

CS(=O)(=O)c1ccc(-c2ccc3ccccc3c2CO)cc1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 9/20 0.53
DRD1 P21728 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2158489 0.87 PSIP1 (0.43) PTGS2CA12CA1CA2CA9
SCHEMBL7913584 0.79 HSD17B10 (0.47)
Acetic Acid SCHEMBL28094250 0.78 HSD17B10 (0.46)
SCHEMBL28181882 0.78 CA12 (0.68) PTGS2DRD1CA12CA1CA2
SCHEMBL2158703 0.78 PTGS2 (0.54) PTGS2CA12CA1CA2CA9
SCHEMBL10897509 0.76 PRKAA2 (0.46)
SCHEMBL7229909 0.76 CYP1A2 (0.51)
SCHEMBL5723494 0.74 PTGS2 (0.65) PTGS2DRD1
Acetic Acid SCHEMBL28094251 0.73 MEN1 (0.47)
Phenol SCHEMBL28221008 0.73 KDM4E (0.47) CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1692101-B1 MERCAPTO-PHENYL-NAPHTHYL-METHANE DERIVATIVES AND PREPARATION THEREOF COUNCIL SCIENT IND RES (IN) 2011-07-06 EP claimed