Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21598078 | 1.00 | LMNA (0.67) | LMNATSHRCYP19A1EGLN3MAPT | |
| SCHEMBL1200642 | 0.82 | LMNA (0.96) | LMNATSHRCYP19A1EGLN3MAPT | |
| Hydrochloric Acid SCHEMBL247629 | 0.80 | LMNA (1.00) | LMNATSHRCYP19A1EGLN3MAPT | |
| SCHEMBL7837590 | 0.74 | LMNA (0.52) | LMNATSHRCYP19A1MAPTKMT2A | |
| SCHEMBL13544733 | 0.74 | LMNA (0.68) | LMNATSHRCYP19A1EGLN3MAPT | |
| SCHEMBL9746578 | 0.72 | LMNA (0.66) | LMNATSHRCYP19A1EGLN3MAPT | |
| SCHEMBL17731478 | 0.72 | LMNA (0.59) | LMNATSHRCYP19A1EGLN3MAPT | |
| SCHEMBL16422647 | 0.71 | LMNA (0.63) | LMNATSHRCYP19A1EGLN3MAPT | |
| SCHEMBL761160 | 0.69 | — | — | |
| SCHEMBL6656012 | 0.69 | LMNA (0.61) | LMNATSHRCYP19A1EGLN3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4464715-A2 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BicycleTx Limited (GB) | 2024-11-20 | — | — | EP | claimed |
| EP-3810169-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BicycleTX Limited (GB) | 2021-04-28 | — | — | EP | claimed |
| CN-112601539-A | Bicyclic peptide ligands specific for bindin-4 | 拜斯科技术开发有限公司 | 2021-04-02 | — | — | CN | claimed |
| WO-2019243832-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BICYCLETX LIMITED (GB) | 2019-12-26 | — | — | WO | claimed |
| US-12459974-B2 | Bicyclic peptide ligands specific for Nectin-4 | BICYCLETX LIMITED (GB) | 2025-11-04 | — | — | US | disclosed |
| US-20250263438-A9 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BICYCLETX LIMITED (GB) | 2025-08-21 | — | — | US | disclosed |
| EP-4588934-A2 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BicycleTX Limited (GB) | 2025-07-23 | — | — | EP | disclosed |
| US-20250066421-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BICYCLETX LIMITED (GB) | 2025-02-27 | — | — | US | disclosed |
| US-20250051392-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BICYCLETX LIMITED (GB) | 2025-02-13 | — | — | US | disclosed |
| US-20250002536-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BICYCLETX LIMITED (GB) | 2025-01-02 | — | — | US | disclosed |
| US-20240400608-A1 | SYNTHESIS OF BICYCLE TOXIN CONJUGATES, AND INTERMEDIATES THEREOF | BricycleTx Limited (GB) | 2024-12-05 | — | — | US | disclosed |
| EP-4464715-A2 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BicycleTx Limited (GB) | 2024-11-20 | — | — | EP | disclosed |
| CN-118103075-A | Synthesis of bicyclic peptide toxin conjugates and intermediates thereof | 拜斯科技术开发有限公司 | 2024-05-28 | — | — | CN | disclosed |
| EP-3810169-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BicycleTX Limited (GB) | 2021-04-28 | — | — | EP | disclosed |
| CN-112601539-A | Bicyclic peptide ligands specific for bindin-4 | 拜斯科技术开发有限公司 | 2021-04-02 | — | — | CN | disclosed |
| WO-2019243832-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | BICYCLETX LIMITED (GB) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12459974-B2 | Bicyclic peptide ligands specific for Nectin-4 | NECTIN4, VCAM1, SIGLEC7 | LMNA 2666/4885TSHR 2286/4885CYP19A1 4777/4885 |
| US-20250002536-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | NECTIN4, VCAM1, SIGLEC7 | LMNA 2666/4885TSHR 2286/4885CYP19A1 4777/4885 |
| US-20240400608-A1 | SYNTHESIS OF BICYCLE TOXIN CONJUGATES, AND INTERMEDIATES THEREOF | BTD, ANTXR2, CYCS | LMNA 592/4885TSHR 1914/4885CYP19A1 405/4885 |
| US-20250051392-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | NECTIN4, VCAM1, SIGLEC7 | LMNA 2666/4885TSHR 2286/4885CYP19A1 4777/4885 |
| US-20250263438-A9 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | NECTIN4, VCAM1, SIGLEC7 | LMNA 2666/4885TSHR 2286/4885CYP19A1 4777/4885 |
| US-20250066421-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 | NECTIN4, VCAM1, SIGLEC7 | LMNA 2666/4885TSHR 2286/4885CYP19A1 4777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.