Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8331728 | 0.86 | ALOX5 (0.46) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL8333598 | 0.84 | SLC9A1 (0.52) | HTR2CHTR2AHTR2BSLC6A3ALOX5 | |
| SCHEMBL8330436 | 0.84 | KDM1A (0.51) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL8332790 | 0.82 | SLC9A1 (0.56) | HTR2CHTR2AHTR2BALOX5PARP1 | |
| SCHEMBL27430078 | 0.80 | SLC9A1 (0.56) | ALOX5SLC9A1MEN1ALDH1A1KMT2A | |
| SCHEMBL8331608 | 0.80 | HTR2A (0.45) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL29303274 | 0.75 | HTR2A (0.51) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL21600643 | 0.73 | HTR2C (0.49) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL8487182 | 0.72 | MTNR1A (0.39) | ALOX5KDM1AKDM4EMEN1GAA | |
| SCHEMBL25005715 | 0.72 | PARP1 (0.53) | ALOX5KDM1APARP1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753709-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-19 | — | — | US | disclosed |