Benzene

Benzene

SCHEMBL8775366

O=CCCCC(=O)C(=O)O.c1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 2/20 0.46
MAPK1 P28482 1/20 0.46
SLC13A3 Q8WWT9 1/20 0.46
EGLN1 Q9GZT9 1/20 0.46
HIF1A Q16665 1/20 0.41
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
TSHR P16473 2/20 0.35
PPARG P37231 3/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP19A1 P11511 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1296671 0.95 OR51E2 (0.50) OR51E2MAPK1SLC13A3EGLN1HIF1A
SCHEMBL14386822 0.88 MAPK1 (0.48) OR51E2MAPK1SLC13A3EGLN1HIF1A
SCHEMBL11678127 0.86 MAPK1 (0.46) OR51E2MAPK1SLC13A3EGLN1HIF1A
SCHEMBL21600769 0.86 MAPK1 (0.46) OR51E2MAPK1SLC13A3EGLN1HIF1A
SCHEMBL28777797 0.86 MAPK1 (0.46) OR51E2MAPK1SLC13A3EGLN1HIF1A
SCHEMBL23174677 0.86 MAPK1 (0.46) OR51E2MAPK1SLC13A3EGLN1HIF1A
SCHEMBL2441490 0.82 MAPK1 (0.54) OR51E2MAPK1SLC13A3EGLN1TSHR
SCHEMBL1331668 0.82 HIF1A (0.53) EGLN1HIF1ATSHRALDH1A1MAPT
SCHEMBL665744 0.79 OR51E2 (0.55) OR51E2MAPK1SLC13A3EGLN1HIF1A
SCHEMBL60431 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0496555-B1 Corrosion-inhibiting coating compositions CIBA GEIGY AG (CH) 1997-11-19 EP disclosed
US-5277709-A Film forming binder and corrosion inhibitor CIBA-GEIGY CORPORATION (US) 1994-01-11 US disclosed