Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL215048 | 0.81 | ALDH1A1 (0.60) | LMNAALOX15PTPN7KDM4EMEN1 | |
| SCHEMBL7996336 | 0.80 | LMNA (0.63) | LMNAALOX15PTPN7KDM4EMEN1 | |
| SCHEMBL29955055 | 0.80 | LMNA (0.63) | LMNAALOX15PTPN7KDM4EMEN1 | |
| SCHEMBL7334512 | 0.80 | ESR1 (0.55) | LMNAALOX15KDM4EMEN1KMT2A | |
| SCHEMBL214282 | 0.78 | CRHBP (0.55) | LMNAALOX15PTPN7MAPK1PPARA | |
| SCHEMBL6445977 | 0.78 | KMT2A (0.47) | KDM4EMEN1KMT2AALDH1A1ATM | |
| SCHEMBL413254 | 0.76 | LMNA (0.81) | LMNAALOX15PTPN7KDM4EMEN1 | |
| SCHEMBL23142738 | 0.75 | KDM4E (0.46) | KDM4EMEN1KMT2AALDH1A1ATM | |
| SCHEMBL29607044 | 0.75 | KDM4E (0.46) | KDM4EMEN1KMT2AALDH1A1ATM | |
| SCHEMBL5830773 | 0.75 | PPARA (0.56) | LMNAALOX15PTPN7KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2337820-B1 | AZO DYES, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF | HUNTSMAN ADV MAT SWITZERLAND (CH) | 2013-05-15 | — | — | EP | disclosed |
| US-8088182-B2 | Azo dyes, a process for the preparation thereof and the use thereof | HUNTSMAN INTERNATIONAL LLC (US) | 2012-01-03 | — | — | US | disclosed |
| US-20110197377-A1 | AZO DYES, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF | HUNTSMAN INTERNATIONAL LLC (US) | 2011-08-18 | — | — | US | disclosed |
| EP-2337820-A2 | AZO DYES, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF | Huntsman Advanced Materials (Switzerland) GmbH (CH) | 2011-06-29 | — | — | EP | disclosed |
| WO-2010046192-A2 | AZO DYES, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2010-04-29 | — | — | WO | disclosed |