SCHEMBL2160280

SCHEMBL2160280

C[Si](C)(C)N(C(=O)O)[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11371340 0.69 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL50594 0.69 CHRM2 (0.34)
SCHEMBL10839180 0.69 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL273694 0.69 LMNA (0.35) ALDH1A1
SCHEMBL3458095 0.69
SCHEMBL21184390 0.67
SCHEMBL19547612 0.67
SCHEMBL21633440 0.67
SCHEMBL22050834 0.65 TDP1 (0.35) ALDH1A1FFAR3
SCHEMBL1101045 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115611929-A Copper-nitrogen heterocyclic carbene metal complex and method for catalytic synthesis of beta alkenyl borate by using same 陕西科技大学 2023-01-17 CN claimed
EP-3281941-B1 PROCESS FOR PREPARING 2-(5-BROMO-4-(1-CYCLOPROPYLNAPHTHALEN-4-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACETIC ACID ZENTIVA KS (CZ) 2019-07-24 EP claimed
EP-3281941-A1 PROCESS FOR PREPARING 2-(5-BROMO-4-(1-CYCLOPROPYLNAPHTHALEN-4-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACETIC ACID Zentiva K.S. (CZ) 2018-02-14 EP claimed
WO-2015175521-A1 METHOD AND SYSTEM TO IMPROVE DRYING OF FLEXIBLE NANO-STRUCTURES TOKYO ELECTRON LIMITED (JP) 2015-11-19 WO claimed
EP-2354165-A1 Aeropolysaccharides, composites and preparation thereof Technion Research and Development Foundation, Ltd. (IL) 2011-08-10 EP claimed
US-20110180751-A1 AEROPOLYSACCHARIDES, COMPOSITES AND PREPARATION THEREOF TECHNION R&D FOUNDATION LTD. (IL) 2011-07-28 US claimed
EP-1971623-B1 METHOD FOR PRODUCING LIQUID, STORAGE-STABLE ORGANIC ISOCYANATES COMPRISING CARBODIIMIDE AND/OR URETONIMINE GROUPS BAYER MATERIALSCIENCE AG (DE) 2009-09-16 EP claimed
EP-1971623-A2 METHOD FOR PRODUCING LIQUID, STORAGE-STABLE ORGANIC ISOCYANATES COMPRISING CARBODIIMIDE AND/OR URETONIMINE GROUPS Bayer MaterialScience AG (DE) 2008-09-24 EP claimed
WO-2007077000-A2 METHOD FOR PRODUCING LIQUID, STORAGE-STABLE ORGANIC ISOCYANATES COMPRISING CARBODIIMIDE AND/OR URETONIMINE GROUPS BAYER MATERIALSCIENCE AG (DE) 2007-07-12 WO claimed
WO-2001007485-A1 METHOD FOR CARRYING OUT THE TARGETED DEPOLYMERIZATION OF POLYSACCHARIDES RHODIA ACETOW GMBH (DE) 2001-02-01 WO claimed
EP-0034394-B1 PROCESS FOR THE PREPARATION OF 3'-BROMOSUBSTITUTED DEACETOXYCEPHALOSPORANIC ACID SULPHOXIDE DERIVATIVES GIST-BROCADES N.V. (NL) 1984-08-01 EP claimed
WO-2023141593-A2 PROCESS FOR SYNTHESIS OF GALBULIMIMA ALKALOID 18 AND COMPOUNDS USEFUL AS OPIOID RECEPTOR ANTAGONISTS AND AGONISTS THE SCRIPPS RESEARCH INSTITUTE (US) 2023-07-27 WO disclosed
CN-115611929-A Copper-nitrogen heterocyclic carbene metal complex and method for catalytic synthesis of beta alkenyl borate by using same 陕西科技大学 2023-01-17 CN disclosed
EP-3281941-B1 PROCESS FOR PREPARING 2-(5-BROMO-4-(1-CYCLOPROPYLNAPHTHALEN-4-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACETIC ACID ZENTIVA KS (CZ) 2019-07-24 EP disclosed
EP-3281941-A1 PROCESS FOR PREPARING 2-(5-BROMO-4-(1-CYCLOPROPYLNAPHTHALEN-4-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACETIC ACID Zentiva K.S. (CZ) 2018-02-14 EP disclosed
EP-0305111-A2 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions BEECHAM GROUP PLC (GB) 1989-03-01 EP disclosed
EP-0265185-A2 Cephalosporins, processes for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1988-04-27 EP disclosed
EP-0000078-B1 PREPARATION OF SALTS OF HYDROXYPHOSPHINYLUREIDOBENZYLPENICILLINS. GIST-BROCADES N.V. (NL) 1980-07-23 EP disclosed
US-4177189-A REACTION WITH AN ALKYL HALOPHOSPHORUS ISOCYANATIDATE GIST-BROCADES N.V. (NL) 1979-12-04 US disclosed
EP-0000078-A1 Preparation of salts of hydroxyphosphinylureidobenzylpenicillins. GIST-BROCADES N.V. (NL) 1978-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110180751-A1 AEROPOLYSACCHARIDES, COMPOSITES AND PREPARATION THEREOF ALG1, CHIT1, ARSA ALDH1A1 365/4885TSHR 4726/4885FFAR3 4081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.