SCHEMBL216030

SCHEMBL216030

C=CC(C)[SiH](OC(C)=O)OC(C)=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4951104 0.72 ALDH1A1 (0.30) ALDH1A1
SCHEMBL703630 0.72 TSHR (0.41) TSHRALDH1A1
SCHEMBL21294330 0.70 TSHR (0.31) TSHR
SCHEMBL143501 0.67
SCHEMBL2950746 0.65 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL1324823 0.65
SCHEMBL2246474 0.65
SCHEMBL6699198 0.65 TSHR (0.35) TSHR
SCHEMBL5359678 0.65 TSHR (0.35) TSHRALDH1A1
SCHEMBL2771869 0.65 ALDH1A1 (0.44) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7527870-B2 Organosiloxane compositions DOW CORNING CORPORATION (US) 2009-05-05 US claimed
EP-1620491-B1 MOISTURE CURABLE ORGANOSILOXANE COMPOSITIONS DOW CORNING (US) 2007-04-25 EP claimed
US-20060194067-A1 Organosiloxane compositions DOW SILICONES CORPORATION 2006-08-31 US claimed
EP-1620491-A1 MOISTURE CURABLE ORGANOSILOXANE COMPOSITIONS Dow Corning Corporation (US) 2006-02-01 EP claimed
WO-2004094503-A1 MOISTURE CURABLE ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2004-11-04 WO claimed
EP-0477765-A2 Thermoplastic, coupled barrier composites THE B.F. GOODRICH COMPANY (US) 1992-04-01 EP claimed
US-12552905-B2 Additive stabilization DOW SILICONES CORPORATION (US) 2026-02-17 US disclosed
EP-4204477-B1 POLYDIORGANOSILOXANE PREPARATION DOW SILICONES CORP (US) 2025-08-13 EP disclosed
EP-4222191-B1 ADDITIVE STABILIZATION DOW SILICONES CORP (US) 2024-10-09 EP disclosed
US-20230365763-A1 ADDITIVE STABILIZATION DOW SILICONES CORPORATION 2023-11-16 US disclosed
US-20230323034-A1 POLYDIORGANOSILOXANE PREPARATION DOW SILICONES CORPORATION 2023-10-12 US disclosed
US-20230272167-A1 SILICONE SEALANT PREPARATION DOW SILICONES CORPORATION 2023-08-31 US disclosed
US-20230272168-A1 POLYDIORGANOSILOXANE PREPARATION DOW SILICONES CORPORATION 2023-08-31 US disclosed
US-5091440-A Acrylate- or methacrylate-functional organopolysiloxanes WACKER SILICONES CORPORATION (US) 1992-02-25 US disclosed
US-4749803-A Reaction products of mercapto-functional monohydric alcohols and vinyl silanes, and NCO-functional compounds therefrom PPG INDUSTRIES, INC. (US) 1988-06-07 US disclosed
US-4720534-A NCO-terminated compounds from adducts of mercapto-functional polyhydric alcohols and vinyl-type silanes containing hydrolyzable groups PPG INDUSTRIES, INC. (US) 1988-01-19 US disclosed
EP-0231514-A2 Compositions based on resins having silicon atoms attached to hydrolyzable groups derived from vinyl silanes and mercaptofunctional compounds PPG INDUSTRIES, INC. (US) 1987-08-12 EP disclosed
EP-0229390-A2 Reaction products of mercapto-functional monohydric alcohols and vinyl silanes, and NCO-functional compounds therefrom PPG INDUSTRIES, INC. (US) 1987-07-22 EP disclosed
US-4652610-A FLEXIBLE COATINGS; AUTOMOBILE PAINTS PPG INDUSTRIES, INC. (US) 1987-03-24 US disclosed
US-4652664-A Addition products prepared from mercapto-functional polyhydric alcohols and vinyl-type silanes containing hydrolyzable groups PPG INDUSTRIES, INC. (US) 1987-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552905-B2 Additive stabilization RCC1, SCO2, DDT TSHR 3602/4885ALDH1A1 334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.