SCHEMBL21603012

SCHEMBL21603012

CNC(=O)C(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.53
KMT2A Q03164 2/20 0.50
MDM4 O15151 2/20 0.50
TP53 P04637 2/20 0.50
EPHX2 P34913 1/20 0.50
MDM2 Q00987 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6746183 0.90 KMT2A (0.60) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL10137531 0.85 KMT2A (0.52) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL24579463 0.85 KMT2A (0.52) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL18475149 0.84 KMT2A (0.51) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL13697523 0.83 MDM4 (0.48) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL16294410 0.83 CASP3 (0.59) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL16294412 0.83 CASP3 (0.59) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL12206292 0.82 CASP3 (0.50) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL14374784 0.82 PTPN1 (0.50) CASP3MDM4TP53
SCHEMBL13252047 0.82 PTPN1 (0.50) CASP3MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12157717-B2 Compounds for the treatment of bovine or swine respiratory disease INTERVET INC. (US) 2024-12-03 US disclosed
US-20210347730-A1 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE INTERVET INC. (US) 2021-11-11 US disclosed
EP-3810571-A1 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE Intervet International B.V. (NL) 2021-04-28 EP disclosed
WO-2020002238-A1 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE INTERVET INTERNATIONAL B.V. (NL) 2020-01-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210347730-A1 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE PIGS, BTD, PPARD CASP3 1951/4885KMT2A 4524/4885MDM4 4715/4885
US-12157717-B2 Compounds for the treatment of bovine or swine respiratory disease PIGS, BTD, PPARD CASP3 1951/4885KMT2A 4524/4885MDM4 4715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.