Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 2/20 | 0.56 |
| ▸ | MDM4 | O15151 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.49 |
| ▸ | FABP7 | O15540 | 1/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21603012 | 0.90 | CASP3 (0.53) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL118016 | 0.88 | KMT2A (0.57) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL30208674 | 0.88 | KMT2A (0.57) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL8892308 | 0.88 | KMT2A (0.57) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL14098623 | 0.87 | KMT2A (0.56) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL13784428 | 0.87 | KMT2A (0.56) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL24628028 | 0.86 | MDM4 (0.56) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL8895610 | 0.86 | MDM4 (0.62) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL119043 | 0.86 | CASP3 (0.57) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL178736 | 0.86 | CASP3 (0.57) | KMT2ACASP3MDM4TP53EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040086949-A1 | Method for preparing a ligand presenting assembly (LPA), an LPA and uses thereof | STATENS SERUM INSTITUT | 2004-05-06 | — | — | US | disclosed |
| EP-1117677-B1 | LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF | STATENS SERUMINSTITUT (DK) | 2003-11-12 | — | — | EP | disclosed |