Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31401142 | 0.77 | MAPT (0.35) | LMNAMAPTHTTBLM | |
| SCHEMBL22040912 | 0.71 | CYP2C19 (0.38) | — | |
| SCHEMBL22040917 | 0.71 | CYP2C19 (0.38) | — | |
| SCHEMBL22040915 | 0.71 | CYP2C19 (0.38) | — | |
| SCHEMBL19729054 | 0.69 | LTB4R (0.37) | LMNAMAPTHTTGABRA1 | |
| SCHEMBL17865232 | 0.69 | HTR2B (0.41) | LMNA | |
| SCHEMBL28917603 | 0.69 | ALDH1A1 (0.40) | MAPTHTT | |
| SCHEMBL8250970 | 0.69 | TSHR (0.40) | — | |
| SCHEMBL22482296 | 0.67 | KDM1A (0.33) | — | |
| SCHEMBL2177894 | 0.66 | HTR2C (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020004521-A1 | THERAPEUTIC AGENT FOR INFLAMMATORY DISEASES, AUTOIMMUNE DISEASES, FIBROTIC DISEASES, AND CANCER DISEASES | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 2020-01-02 | — | — | WO | disclosed |