Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21603780 | 0.94 | MEN1 (0.41) | ALDH1A1HIF1AMAPK1LMNAMAPT | |
| SCHEMBL15031976 | 0.82 | ALDH1A1 (0.40) | ALDH1A1HIF1AMAPK1MAPTHPGD | |
| SCHEMBL18117485 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MAPK1LMNAMAPTHPGD | |
| SCHEMBL13569707 | 0.73 | ALDH1A1 (0.41) | ALDH1A1MAPK1MAPTHPGDGAA | |
| SCHEMBL23800895 | 0.73 | CYP1A2 (0.36) | ALDH1A1MAPK1MAPTHPGDGAA | |
| SCHEMBL21419520 | 0.71 | HTT (0.39) | ALDH1A1MAPK1LMNAMAPTHPGD | |
| SCHEMBL21604205 | 0.71 | MAPT (0.57) | ALDH1A1LMNAMAPTHPGDGAA | |
| SCHEMBL18117472 | 0.68 | KDM4E (0.38) | ALDH1A1HIF1AMAPK1LMNAMAPT | |
| SCHEMBL2096219 | 0.68 | CYP1A2 (0.38) | ALDH1A1HIF1AMAPK1LMNAMAPT | |
| SCHEMBL2731284 | 0.67 | CCR5 (0.33) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | disclosed |