Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23196776 | 0.90 | KDM4E (0.44) | KDM4EHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL19578541 | 0.87 | KDM4E (0.56) | KDM4EHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL20202310 | 0.86 | TSHR (0.39) | KDM4EHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL24240781 | 0.86 | NOTUM (0.55) | KDM4EHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL23196724 | 0.85 | KDM4E (0.42) | KDM4EHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL26224571 | 0.84 | HSD17B3 (0.44) | KDM4EHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL21065872 | 0.84 | NOTUM (0.54) | NOTUMHSD17B3KCNN4KCNA3LMNA | |
| SCHEMBL24993714 | 0.83 | HDAC3 (0.36) | KDM4ETSHRALDH1A1KMT2ANOTUM | |
| SCHEMBL23659145 | 0.82 | MAPT (0.39) | MAPTMTNR1AMTNR1BLMNA | |
| SCHEMBL26217143 | 0.82 | MAPT (0.39) | KDM4EHTTSMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067458-A1 | PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2021-04-08 | — | — | WO | disclosed |
| WO-2019243672-A1 | CONJUGATE | GLYKOS BIOMEDICAL OY (FI) | 2019-12-26 | — | — | WO | disclosed |