Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 8/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21065872 | 0.89 | NOTUM (0.54) | HSD17B3NOTUMKCNN4KCNA3LMNA | |
| SCHEMBL21604411 | 0.84 | KDM4E (0.41) | HSD17B3NOTUMKDM4EKMT2AMEN1 | |
| SCHEMBL19578541 | 0.84 | KDM4E (0.56) | HSD17B3NOTUMKDM4EALDH1A1CYP3A4 | |
| SCHEMBL10962838 | 0.79 | HSD17B3 (0.52) | HSD17B3NOTUMKDM4EKMT2AMEN1 | |
| SCHEMBL24240781 | 0.78 | NOTUM (0.55) | NOTUMKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL20202310 | 0.78 | TSHR (0.39) | NOTUMKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL19889885 | 0.77 | HSD17B3 (0.53) | HSD17B3NOTUMKDM4ESMN1; SMN2HTT | |
| SCHEMBL25961782 | 0.76 | LMNA (0.56) | HSD17B3KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL27349417 | 0.76 | DRD3 (0.38) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22692370 | 0.76 | LMNA (0.41) | NOTUMMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141855-A1 | PROTEIN CONJUGATES WITH MULTIPLE PAYLOADS AND METHODS FOR MAKING THE SAME | GLYCO-THERAPY BIOTECHNOLOGY CO., LTD. (CN) | 2023-08-03 | — | — | WO | disclosed |