Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21604411 | 0.86 | KDM4E (0.41) | TSHRNOTUMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL24240781 | 0.84 | NOTUM (0.55) | TSHRNOTUMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL19578541 | 0.83 | KDM4E (0.56) | TSHRNOTUMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL21284596 | 0.82 | HSD17B3 (0.47) | TSHRNOTUMSMN1; SMN2LMNAMAPT | |
| SCHEMBL22692370 | 0.81 | LMNA (0.41) | TSHRNOTUMLMNAMAPTHSD17B10 | |
| SCHEMBL26217143 | 0.81 | MAPT (0.39) | TSHRNOTUMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL23659145 | 0.81 | MAPT (0.39) | LMNAMAPTHSD17B10 | |
| SCHEMBL21065872 | 0.80 | NOTUM (0.54) | NOTUMLMNA | |
| SCHEMBL26946557 | 0.78 | NOTUM (0.39) | TSHRNOTUMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL26224571 | 0.78 | HSD17B3 (0.44) | TSHRNOTUMKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098390-A1 | ALBUMIN-BINDING PSMA INHIBITORS | CANCER TARGETED TECHNOLOGY LLC (US) | 2018-05-31 | — | — | WO | disclosed |