Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706689 | 0.80 | ALDH1A1 (0.43) | MAPK1ATML3MBTL1LMNAALDH1A1 | |
| SCHEMBL21932249 | 0.75 | MAPK1 (0.38) | MAPK1ATMKDM4EL3MBTL1LMNA | |
| SCHEMBL31065610 | 0.75 | MAPK1 (0.38) | MAPK1ATMKDM4EL3MBTL1LMNA | |
| SCHEMBL21932322 | 0.75 | BRD4 (0.42) | MAPK1ATMKDM4EL3MBTL1LMNA | |
| SCHEMBL31065600 | 0.75 | BRD4 (0.42) | MAPK1ATMKDM4EL3MBTL1LMNA | |
| SCHEMBL705650 | 0.74 | ALDH1A1 (0.43) | ATML3MBTL1LMNAALDH1A1PSMD14 | |
| SCHEMBL21606238 | 0.74 | HSD17B10 (0.53) | ATMKDM4EL3MBTL1LMNAALDH1A1 | |
| SCHEMBL708486 | 0.73 | ALOX15 (0.38) | MAPK1ATML3MBTL1LMNAALDH1A1 | |
| SCHEMBL707735 | 0.73 | ALOX15 (0.56) | ATMKDM4EL3MBTL1LMNAALDH1A1 | |
| SCHEMBL709393 | 0.73 | ALOX15 (0.38) | MAPK1ATMKDM4EL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243823-A1 | AZAHETEROCYCLIC SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LIMITED (GB) | 2019-12-26 | — | — | WO | disclosed |