Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21932249 | 1.00 | MAPK1 (0.38) | MAPK1ATMALOX15HSD17B10KDM4E | |
| SCHEMBL21932259 | 0.77 | LMNA (0.45) | MAPK1ALOX15HSD17B10LMNAALDH1A1 | |
| SCHEMBL21932308 | 0.77 | LMNA (0.45) | MAPK1ALOX15HSD17B10LMNAALDH1A1 | |
| SCHEMBL21932485 | 0.77 | LMNA (0.45) | MAPK1ALOX15HSD17B10LMNAALDH1A1 | |
| SCHEMBL24307314 | 0.76 | ALOX15 (0.41) | MAPK1ATMALOX15HSD17B10KDM4E | |
| SCHEMBL21606264 | 0.75 | MAPK1 (0.40) | MAPK1ATMALOX15HSD17B10KDM4E | |
| SCHEMBL31386670 | 0.74 | ALOX15 (0.45) | MAPK1ATMALOX15HSD17B10KDM4E | |
| SCHEMBL25822020 | 0.74 | ALOX15 (0.45) | MAPK1ATMALOX15HSD17B10KDM4E | |
| SCHEMBL31065600 | 0.73 | BRD4 (0.42) | MAPK1ATMALOX15HSD17B10KDM4E | |
| SCHEMBL21932322 | 0.73 | BRD4 (0.42) | MAPK1ATMALOX15HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132972-B | Small molecule modulators of human STING | 克拉德夫制药有限公司 | 2024-07-12 | — | — | CN | disclosed |