Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21606316 | 0.94 | TSHR (0.47) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL21605321 | 0.87 | CHRM1 (0.38) | TSHRALDH1A1LMNACYP3A4SMN1; SMN2 | |
| SCHEMBL21605318 | 0.82 | PIN1 (0.46) | TSHRALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL21606317 | 0.81 | TSHR (0.46) | TSHRALDH1A1LMNATP53MAPK1 | |
| SCHEMBL27549297 | 0.78 | TSHR (0.54) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL21606283 | 0.76 | TSHR (0.51) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL21606341 | 0.76 | GAA (0.40) | ALDH1A1KDM4EPOLB | |
| SCHEMBL21605322 | 0.75 | HIF1A (0.33) | TSHRALDH1A1MAPK1 | |
| SCHEMBL28119721 | 0.75 | ALDH1A1 (0.75) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL11699142 | 0.75 | NPC1 (0.58) | TSHRALDH1A1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243580-A1 | PHENYLPHOSPHINO COMPOUNDS AS PROCESS STABILIZERS | CLARIANT PLASTICS & COATINGS LTD (CH) | 2019-12-26 | — | — | WO | disclosed |