Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21605321 | 0.84 | CHRM1 (0.38) | ALDH1A1CYP2D6TDP1 | |
| SCHEMBL21605322 | 0.79 | HIF1A (0.33) | ALDH1A1ADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL21606317 | 0.79 | TSHR (0.46) | ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL21606316 | 0.78 | TSHR (0.47) | ALDH1A1TDP1 | |
| SCHEMBL21606343 | 0.77 | AAK1 (0.40) | GAAALDH1A1POLBTDP1 | |
| SCHEMBL21605318 | 0.77 | PIN1 (0.46) | GAAALDH1A1POLBSLC6A3TDP1 | |
| SCHEMBL21606286 | 0.76 | TSHR (0.50) | ALDH1A1KDM4EPOLB | |
| Acetic Acid SCHEMBL9549682 | 0.74 | GAA (0.43) | GAAALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL17680407 | 0.72 | POLB (0.36) | GAAALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL21606279 | 0.71 | APAF1 (0.44) | ALDH1A1KDM4EPOLBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243580-A1 | PHENYLPHOSPHINO COMPOUNDS AS PROCESS STABILIZERS | CLARIANT PLASTICS & COATINGS LTD (CH) | 2019-12-26 | — | — | WO | disclosed |