SCHEMBL21607402

SCHEMBL21607402

CS(=O)(=O)C1CCC(C#N)(CNCl)CC1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RORC P51449 9/20 0.37
SLC6A9 P48067 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21607435 1.00 RORC (0.37) RORCSLC6A9
SCHEMBL23189901 0.80 RORC (0.41) RORCSLC6A9
SCHEMBL28544240 0.78 RORC (0.31) RORC
Hydrochloric Acid SCHEMBL21598022 0.77 RORC (0.31) RORC
SCHEMBL21607712 0.76 SLC6A9 (0.34) SLC6A9
SCHEMBL21606667 0.76 SLC6A9 (0.34) SLC6A9
SCHEMBL21606105 0.75 SLC6A9 (0.36) RORCSLC6A9
SCHEMBL21605619 0.75 SLC6A9 (0.36) RORCSLC6A9
SCHEMBL21607413 0.75 SLC6A9 (0.36) RORCSLC6A9
SCHEMBL23220040 0.74 KDM1A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019243999-A1 PHENYL SUBSTITUTED PYRAZOLES AS MODULATORS OF RORYT JANSSEN PHARMACEUTICA NV (BE) 2019-12-26 WO disclosed