SCHEMBL28544240

SCHEMBL28544240

CS(=O)(=O)C1CCC(C#N)(CN)CC1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL21598022 0.98 RORC (0.31) RORC
SCHEMBL21607402 0.78 RORC (0.37) RORC
SCHEMBL21607435 0.78 RORC (0.37) RORC
SCHEMBL28536649 0.77 RORC (0.33) RORC
SCHEMBL28536645 0.77 RORC (0.33) RORC
SCHEMBL23189901 0.74 RORC (0.41) RORC
SCHEMBL21598369 0.73
SCHEMBL24463780 0.72 ALDH1A1 (0.41)
SCHEMBL18502947 0.72 SLC6A9 (0.30)
SCHEMBL290901 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112566901-A Phenyl-substituted pyrazoles as modulators of ROR γ t 詹森药业有限公司 2021-03-26 CN disclosed