Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.44 |
| ▸ | DTYMK | P23919 | 1/20 | 0.44 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3847987 | 0.93 | POLB (0.52) | POLBKDM4EALDH1A1HTTFNTA | |
| SCHEMBL21608350 | 0.83 | POLB (0.47) | POLBKDM4EALDH1A1DTYMKVEGFA | |
| SCHEMBL20818170 | 0.80 | POLB (0.52) | POLBKDM4EALDH1A1HTTDTYMK | |
| SCHEMBL21607906 | 0.79 | POLB (0.48) | POLBKDM4EALDH1A1DTYMKOPRD1 | |
| SCHEMBL4752726 | 0.78 | POLB (0.53) | POLBKDM4EALDH1A1HTTDTYMK | |
| SCHEMBL30476359 | 0.78 | POLB (0.53) | POLBKDM4EALDH1A1HTTDTYMK | |
| SCHEMBL30476422 | 0.78 | POLB (0.50) | POLBKDM4EALDH1A1HTTDTYMK | |
| SCHEMBL20817749 | 0.78 | POLB (0.50) | POLBKDM4EALDH1A1HTTDTYMK | |
| SCHEMBL892981 | 0.77 | ALDH1A1 (0.54) | KDM4EALDH1A1VEGFAEGLN1OPRD1 | |
| SCHEMBL7274954 | 0.77 | GPR119 (0.51) | POLBKDM4EGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243531-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |