Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 11/20 | 0.35 |
| ▸ | LOX | P28300 | 5/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21608061 | 1.00 | MGLL (0.36) | MGLLLOXL2LOXKHKFFAR1 | |
| SCHEMBL21608074 | 0.94 | LOXL2 (0.39) | MGLLLOXL2LOXKHKCETP | |
| SCHEMBL21607991 | 0.93 | MGLL (0.33) | MGLLLOXL2FFAR1CCR5CETP | |
| SCHEMBL21607983 | 0.93 | MGLL (0.33) | MGLLLOXL2FFAR1CCR5CETP | |
| SCHEMBL21608177 | 0.89 | MGLL (0.35) | MGLLLOXL2LOXFFAR1CETP | |
| SCHEMBL21608183 | 0.89 | MGLL (0.35) | MGLLLOXL2LOXFFAR1CETP | |
| SCHEMBL21608202 | 0.86 | KDM4E (0.34) | — | |
| SCHEMBL21608201 | 0.86 | KDM4E (0.34) | — | |
| SCHEMBL21608034 | 0.86 | KCNK3 (0.37) | MGLLFFAR1CCR5 | |
| SCHEMBL21608031 | 0.86 | KCNK3 (0.37) | MGLLFFAR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243531-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |