Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 5/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18810349 | 0.76 | PDCD1LG2 (0.43) | P2RX7ALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL18809830 | 0.76 | P2RX7 (0.38) | P2RX7ALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL20283719 | 0.73 | BCAT2 (0.34) | BCAT2L3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL4592838 | 0.72 | ALDH1A1 (0.42) | P2RX7L3MBTL1ALDH1A1HPGDMAPT | |
| SCHEMBL2729271 | 0.72 | P2RX7 (0.36) | P2RX7PDCD1LG2CD274 | |
| SCHEMBL2728264 | 0.72 | P2RX7 (0.38) | P2RX7KDM4EPDCD1LG2CD274 | |
| SCHEMBL14660917 | 0.71 | P2RX7 (0.47) | P2RX7MAPT | |
| SCHEMBL21399634 | 0.70 | TAAR1 (0.41) | CTRCTYRKMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL29924487 | 0.70 | TYR (0.47) | BCAT2CTRCTYRALDH1A1HTT | |
| SCHEMBL27740369 | 0.70 | NPC1 (0.40) | CTRCP2RX7L3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-B1 | COMPOUNDS | CTXT PTY LTD (AU) | 2023-11-01 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |