SCHEMBL21609018

SCHEMBL21609018

O=S(=O)(Nc1noc2cccc(Cl)c12)c1cccc2nonc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.52
POLB P06746 2/20 0.51
GFER P55789 1/20 0.51
ALDH1A1 P00352 5/20 0.50
MAPT P10636 2/20 0.50
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MAPK1 P28482 2/20 0.46
TASP1 Q9H6P5 1/20 0.46
HSPD1 P10809 1/20 0.45
PTPN2 P17706 1/20 0.45
PTPN1 P18031 1/20 0.45
PTPN5 P54829 1/20 0.45
HSPE1 P61604 1/20 0.45
MEN1 O00255 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ACLY P53396 1/20 0.43
CCKBR P32239 1/20 0.43
CCR1 P32246 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21609081 0.85 CCKBR (0.42) KMT2APOLBMEN1CCKBR
SCHEMBL21608972 0.84 CTDSP1 (0.61) KMT2APOLBALDH1A1MAPTLMNA
SCHEMBL21608969 0.82 CCR4 (0.43) KMT2APOLBMEN1CCKBR
SCHEMBL21609115 0.81 MEN1 (0.55) KMT2AALDH1A1MAPTGAAMEN1
SCHEMBL29652562 0.80 EDNRA (0.47) KMT2APTPN2PTPN1PTPN5SMN1; SMN2
SCHEMBL21608956 0.80 EDNRA (0.47) KMT2APTPN2PTPN1PTPN5SMN1; SMN2
SCHEMBL21609022 0.79 HTR2A (0.44) CCKBR
SCHEMBL21609121 0.79 EDNRA (0.50) ALDH1A1MAPTLMNAGAAL3MBTL1
SCHEMBL21609098 0.77 KAT6A (0.58) PTPN2PTPN1PTPN5
SCHEMBL21596862 0.76 EDNRB (0.47) KMT2APOLBALDH1A1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 US disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 EP disclosed
EP-3810602-B1 COMPOUNDS CTXT PTY LTD (AU) 2023-11-01 EP disclosed
EP-3810602-B1 COMPOUNDS CTXT PTY LTD (AU) 2023-11-01 EP disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 US disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 US disclosed
US-20200039945-A1 Compounds CTXT PTY LIMITED (AU) 2020-02-06 US disclosed
US-20200039945-A1 Compounds CTXT PTY LIMITED (AU) 2020-02-06 US disclosed
WO-2019243491-A1 COMPOUNDS CTXT PTY LIMITED (AU) 2019-12-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 KMT2A 4165/4885POLB 3605/4885GFER 4363/4885
US-20200039945-A1 Compounds SLC10A1, ABCB11, PCSK9 KMT2A 4165/4885POLB 3604/4885GFER 4361/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B KMT2A 890/4885POLB 4118/4885GFER 3249/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 KMT2A 4165/4885POLB 3604/4885GFER 4361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.