Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.50 |
| ▸ | EDNRB | P24530 | 2/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | TYMS | P04818 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21609028 | 0.88 | BRD4 (0.41) | EDNRAEDNRBKAT6ABRD4CCR4 | |
| SCHEMBL21608956 | 0.84 | EDNRA (0.47) | EDNRAEDNRBKAT6ABRD4CCR4 | |
| SCHEMBL29652562 | 0.84 | EDNRA (0.47) | EDNRAEDNRBKAT6ABRD4CCR4 | |
| SCHEMBL21609115 | 0.82 | MEN1 (0.55) | TYMSTP53ALDH1A1GAAMAPT | |
| SCHEMBL21641942 | 0.81 | BRD4 (0.39) | EDNRAEDNRBKAT6ABRD4CCR4 | |
| SCHEMBL21609098 | 0.81 | KAT6A (0.58) | KAT6ABRD4CCR4PTPN2PTPN1 | |
| SCHEMBL21596862 | 0.81 | EDNRB (0.47) | EDNRAEDNRBKAT6ABRD4ALDH1A1 | |
| SCHEMBL29652493 | 0.79 | PGR (0.46) | KAT6ABRD4CCR4PGRMAPT | |
| SCHEMBL21609106 | 0.79 | PGR (0.46) | KAT6ABRD4CCR4PGRMAPT | |
| SCHEMBL21609018 | 0.79 | KMT2A (0.52) | PTPN2PTPN1PTPN5SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-B1 | COMPOUNDS | CTXT PTY LTD (AU) | 2023-11-01 | — | — | EP | disclosed |
| US-20220153710-A1 | Compounds | CTXT PTY LTD (AU) | 2022-05-19 | — | — | US | disclosed |
| US-20200039945-A1 | Compounds | CTXT PTY LIMITED (AU) | 2020-02-06 | — | — | US | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153710-A1 | Compounds | SLC10A1, ABCB11, PCSK9 | EDNRA 2745/4885EDNRB 2174/4885KAT6A 877/4885 |
| US-20200039945-A1 | Compounds | SLC10A1, ABCB11, PCSK9 | EDNRA 2736/4885EDNRB 2168/4885KAT6A 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.