Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21608846 | 0.82 | PIK3R1 (0.51) | PDE1BHPGDALDH1A1KDM4EALOX15 | |
| SCHEMBL13350 | 0.81 | TBXA2R (0.54) | TSHRMAPK1CNR2TBXA2RNPC1 | |
| SCHEMBL7225918 | 0.79 | MEN1 (0.70) | HPGDALDH1A1KDM4EALOX15HTT | |
| SCHEMBL30934954 | 0.79 | MEN1 (0.70) | HPGDALDH1A1KDM4EALOX15HTT | |
| SCHEMBL7969979 | 0.78 | MAPT (0.50) | SMN1; SMN2MEN1KMT2ACNR2NPC1 | |
| SCHEMBL4042951 | 0.74 | PDE5A (0.54) | PDE1BHPGDALDH1A1KDM4EALOX15 | |
| SCHEMBL19987318 | 0.72 | KDM4E (0.68) | KDM4ECNR2NPC1MAPTNLRP3 | |
| SCHEMBL12004096 | 0.72 | KDM4E (0.52) | KDM4ECNR2TBXA2RCCR2NPC1 | |
| SCHEMBL31588700 | 0.72 | TDP1 (0.60) | HPGDALDH1A1KDM4EALOX15HTT | |
| SCHEMBL9980488 | 0.71 | PDE1B (0.56) | PDE1BHPGDALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243525-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |