Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21609030 | 0.86 | SMN1; SMN2 (0.49) | NPC1RAB9AMAPTTSHRMAPK1 | |
| SCHEMBL21609250 | 0.81 | KAT7 (0.38) | NPC1RAB9ATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL21609264 | 0.79 | MEN1 (0.38) | NPC1RAB9AMAPTRXFP1MEN1 | |
| SCHEMBL21609150 | 0.75 | KAT6A (0.56) | SMN1; SMN2BRD4 | |
| SCHEMBL21609154 | 0.72 | EPHX2 (0.49) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL21609254 | 0.68 | KAT6A (0.37) | RAB9AMAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL18546038 | 0.68 | CA12 (0.47) | NPC1RAB9AMAPTRXFP1TSHR | |
| SCHEMBL18697150 | 0.68 | MAPT (0.47) | NPC1RAB9AMAPTTP53 | |
| SCHEMBL21609048 | 0.67 | STK17B (0.39) | RAB9AMEN1KMT2ASMN1; SMN2KCNH2 | |
| SCHEMBL12426070 | 0.66 | MAPT (0.46) | NPC1RAB9AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |