Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21609154 | 0.86 | EPHX2 (0.49) | SMN1; SMN2MAPTTP53KAT6AHIF1A | |
| SCHEMBL21609153 | 0.86 | NPC1 (0.37) | SMN1; SMN2MAPTTP53MAPK1KDM4E | |
| SCHEMBL21609250 | 0.78 | KAT7 (0.38) | SMN1; SMN2KAT6AHIF1ACHRNA7HTR3A | |
| SCHEMBL21609237 | 0.78 | KAT6A (0.46) | SMN1; SMN2MAPTTP53KAT6AHIF1A | |
| SCHEMBL21609173 | 0.75 | KAT6A (0.48) | SMN1; SMN2MAPTTP53KAT6ACHRNA7 | |
| SCHEMBL21609026 | 0.74 | KAT6A (0.67) | SMN1; SMN2MAPTTP53KAT6AALDH1A1 | |
| SCHEMBL4936083 | 0.72 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTTP53HIF1AALDH1A1 | |
| SCHEMBL29652452 | 0.71 | KAT6A (0.78) | SMN1; SMN2MAPTTP53KAT6AALDH1A1 | |
| SCHEMBL21609114 | 0.71 | KAT6A (0.78) | SMN1; SMN2MAPTTP53KAT6AALDH1A1 | |
| SCHEMBL30667310 | 0.70 | EPHX2 (0.61) | SMN1; SMN2MAPTTP53KAT6AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |