Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21609030 | 0.86 | SMN1; SMN2 (0.49) | EPHX2KAT6AHIF1AMAPTTP53 | |
| SCHEMBL21609091 | 0.78 | KAT7 (0.38) | EPHX2KAT6AMAPTTP53SMN1; SMN2 | |
| SCHEMBL21609237 | 0.76 | KAT6A (0.46) | EPHX2KAT6AHIF1AMAPTTP53 | |
| SCHEMBL21609152 | 0.75 | KAT6A (0.65) | EPHX2KAT6AKMT2A | |
| SCHEMBL21609173 | 0.73 | KAT6A (0.48) | KAT6AMAPTTP53SMN1; SMN2KDM4E | |
| SCHEMBL21609153 | 0.72 | NPC1 (0.37) | MAPTTP53SMN1; SMN2STK17BKCNA5 | |
| SCHEMBL21609103 | 0.67 | KCNA5 (0.44) | KAT6AHIF1ATP53SMN1; SMN2KCNA5 | |
| SCHEMBL21609143 | 0.67 | KCNA5 (0.44) | KAT6AHIF1ATP53SMN1; SMN2KCNA5 | |
| SCHEMBL21609182 | 0.66 | KAT6A (0.41) | KAT6AMAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL2767665 | 0.64 | EPHX2 (0.48) | EPHX2KAT6AMAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |