SCHEMBL21609263

SCHEMBL21609263

CCc1ccc(OC)c(SNc2noc3ccc(C(N)=O)cc23)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STK17B O94768 1/20 0.39
MAPK1 P28482 1/20 0.39
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
SMPD1 P17405 1/20 0.37
MAPT P10636 4/20 0.37
HTT P42858 1/20 0.36
KAT7 O95251 1/20 0.36
KAT6B Q8WYB5 1/20 0.36
KAT6A Q92794 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35
TUBB4B P68371 1/20 0.35
TUBB3 Q13509 1/20 0.35
TUBB2A Q13885 1/20 0.35
TUBB8 Q3ZCM7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21609142 0.90 CCNC (0.43) STK17BPOLBSMN1; SMN2SMPD1MAPT
SCHEMBL21609058 0.89 STK17B (0.36) STK17BPOLBSMN1; SMN2SMPD1MAPT
SCHEMBL21609264 0.84 MEN1 (0.38) STK17BPOLBMAPTHTTKAT7
SCHEMBL21609182 0.81 KAT6A (0.41) POLBSMN1; SMN2MAPTKAT7KAT6B
SCHEMBL21609160 0.80 KAT6A (0.55) SMN1; SMN2KAT7KAT6BKAT6A
SCHEMBL21609008 0.77 BRD4 (0.38) POLBMAPTKAT7KAT6BKAT6A
SCHEMBL21609254 0.76 KAT6A (0.37) STK17BPOLBSMN1; SMN2MAPTKAT7
SCHEMBL21609102 0.75 KAT6A (0.37) MAPK1POLBSMN1; SMN2SMPD1MAPT
SCHEMBL21609091 0.74 KAT7 (0.38) SMN1; SMN2SMPD1MAPTKAT7KAT6B
SCHEMBL21609044 0.74 HTR3A (0.41) KAT7KAT6BKAT6ATUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3810602-B1 COMPOUNDS CTXT PTY LTD (AU) 2023-11-01 EP disclosed
WO-2019243491-A1 COMPOUNDS CTXT PTY LIMITED (AU) 2019-12-26 WO disclosed