SCHEMBL21609008

SCHEMBL21609008

CCc1ccc(OC)c(SNc2noc3cc(Br)ccc23)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 6/20 0.38
TP53 P04637 2/20 0.37
MAPT P10636 2/20 0.37
KAT7 O95251 8/20 0.36
KAT6A Q92794 8/20 0.36
KAT6B Q8WYB5 4/20 0.36
KAT5 Q92993 2/20 0.36
KAT8 Q9H7Z6 2/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36
TUBA3E Q6PEY2 1/20 0.36
TUBA1A Q71U36 1/20 0.36
TUBA1C Q9BQE3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21609182 0.92 KAT6A (0.41) TP53MAPTKAT7KAT6AKAT6B
SCHEMBL21609091 0.85 KAT7 (0.38) TP53MAPTKAT7KAT6AKAT6B
SCHEMBL21609044 0.84 HTR3A (0.41) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21609264 0.82 MEN1 (0.38) BRD4TP53MAPTKAT7KAT6A
SCHEMBL29652572 0.77 KAT6A (0.59) BRD4KAT7KAT6AKAT6BKAT5
SCHEMBL21609043 0.77 KAT6A (0.59) BRD4KAT7KAT6AKAT6BKAT5
SCHEMBL21609263 0.77 STK17B (0.39) TP53MAPTKAT7KAT6AKAT6B
SCHEMBL21609257 0.77 TUBB4A (0.36) TP53MAPTKAT7KAT6AKAT6B
SCHEMBL21609175 0.76 KAT6A (0.39) TP53MAPTKAT7KAT6AKAT6B
SCHEMBL21608997 0.75 KAT7 (0.35) TP53MAPTKAT7KAT6AKAT6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3810602-B1 COMPOUNDS CTXT PTY LTD (AU) 2023-11-01 EP disclosed
WO-2019243491-A1 COMPOUNDS CTXT PTY LIMITED (AU) 2019-12-26 WO disclosed