Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024849 | 0.89 | PRKDC (0.40) | PRKDCKCNH2ACHES1PR1S1PR3 | |
| SCHEMBL8020513 | 0.80 | ACHE (0.36) | PRKDCKCNH2ACHE | |
| SCHEMBL5208805 | 0.76 | MEN1 (0.41) | KMT2AMEN1 | |
| SCHEMBL31082195 | 0.75 | PLAU (0.35) | KCNH2ACHEKMT2AMEN1 | |
| SCHEMBL23293402 | 0.73 | ACHE (0.45) | PRKDCKCNH2ACHES1PR1S1PR3 | |
| SCHEMBL30616739 | 0.73 | ACHE (0.45) | PRKDCKCNH2ACHES1PR1S1PR3 | |
| SCHEMBL8710227 | 0.70 | CYP3A4 (0.36) | ACHEKMT2AMEN1 | |
| SCHEMBL31082087 | 0.69 | MEN1 (0.35) | KCNH2KMT2AMEN1TRPM8 | |
| SCHEMBL1631148 | 0.69 | ACHE (0.47) | PRKDCKCNH2ACHES1PR1S1PR3 | |
| SCHEMBL2370946 | 0.68 | CHRNB2 (0.47) | KMT2AMEN1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020002087-A1 | SUBSTITUTED 3-HETEROARYLOXYPYRIDINES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-02 | — | — | WO | disclosed |
| WO-2020002087-A1 | SUBSTITUTED 3-HETEROARYLOXYPYRIDINES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-02 | — | — | WO | disclosed |