Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 9/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25560521 | 0.87 | RXRA (0.39) | MRGPRX4RXRARXRBRXRGCES2 | |
| SCHEMBL21609799 | 0.86 | NOTUM (0.55) | MRGPRX4CES2NOTUM | |
| SCHEMBL25560524 | 0.84 | CES2 (0.44) | MRGPRX4RXRARXRBRXRGCES2 | |
| SCHEMBL16729402 | 0.81 | AURKA (0.49) | MRGPRX4RXRARXRBRXRGCES2 | |
| SCHEMBL30043488 | 0.79 | AURKA (0.43) | MRGPRX4AURKATPX2 | |
| SCHEMBL26146868 | 0.79 | AURKA (0.43) | MRGPRX4AURKATPX2 | |
| SCHEMBL25178850 | 0.79 | PLA2G2A (0.40) | MRGPRX4NOTUMPLA2G2A | |
| SCHEMBL30043721 | 0.79 | TPMT (0.48) | MRGPRX4RXRARXRBPLA2G2A | |
| SCHEMBL25185967 | 0.79 | TPMT (0.48) | MRGPRX4RXRARXRBPLA2G2A | |
| SCHEMBL30043822 | 0.79 | PLA2G2A (0.40) | MRGPRX4NOTUMPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814332-B1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| EP-3814332-B1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| EP-3814332-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-05 | — | — | EP | disclosed |
| CN-112351978-A | Pesticidally active azole-amide compounds | 先正达参股股份有限公司 | 2021-02-09 | — | — | CN | disclosed |
| WO-2020002563-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-01-02 | — | — | WO | disclosed |
| WO-2020002563-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-01-02 | — | — | WO | disclosed |